For Manchester United, it's hard to see how the first game of the season could have gone much better.
United manager Jose Mourinho paid a British record £75 million ($96 million, 82 million euros) to sign Lukaku from Everton in the close-season and the 24-year-old needed just 33 minutes to get off the mark for his new club.
Lukaku was denied a hat-trick goal on 61 minutes when he was teed up by Mkhitarayan down the right of the area, but Pablo Zabaleta did well to block his goal-bound strike.
Paris Saint-Germain full-back Serge Aurier has also been linked with a move to Old Trafford.
The West Ham season opener is upon is, with a halftime analysis coming up after the opening 45. Potential champions? You wouldn't bet your mortgage against it happening.
ROMELU LUKAKU hailed his flawless debut as a dream come true after firing Manchester United to all three points.
Matic was superb on his Old Trafford debut, breaking up play and feeding the likes of Romelu Lukaku and Marcus Rashford from the centre.
Last season they've met three times and Manchester were better in two games, while third one ended in a draw.
As the crowd serenaded Mourinho and Joe Hart, West Ham's new goalkeeper, was reminded that it was a long way down since he was winning championships with Manchester City, it did not seem to matter too much that Victor Lindelof, the home team's £31m acquisition from Benfica, was not even in the squad because of an unimpressive pre-season. Once the most expensive player in the world, he is now free of that tag.
Hernández scored 37 goals in 103 league games during his days in Manchester and one imagines he would have loved the kind of chances that Lukaku's team-mates served up for the Belgian. Rashford's beautifully weighted pass for the first was another.
United's defense was given an easy ride with Matic stationed in front of them, and Pogba could also thrive this season.
The Belgium worldwide nearly grabbed his hat-trick just after the hour mark following a blistering counter attack from the Red Devils, although Lukaku was unable to cap off the move with a goal as his shot was well blocked by Joe Hart.
Slaven Bilic had clearly set up his side to be compact and frustrate the home side, but Mourinho's men were in a rampant mood as they laid siege to the West Ham goal.