As of Tuesday morning, an appeals court rejected argments from Otte that he shouldn't be put to death because of his age at the time of the crime.
Lawyers for Otte wanted the court to apply the ruling of a Kentucky court last month that found the death penalty unconstitutional for people who were under 21 at the time their crimes were committed.
The death row inmate was sentenced to death for the February 1992 robbery-turned murders of Robert Wasikowski and Sharon Kostura.
An Ohio man convicted of back-to-back murders 25 years ago sang a hymn as he was executed Wednesday morning, media witnesses reported.
"The current scientific understanding of adolescent development underscores why their moral culpability is reduced making them categorically exempt from the death penalty", his attorneys argued. The court didn't indicate when it would rule, though an early Wednesday decision was likely.
Otte's drug addiction, intoxication and depression led to the slayings, and Otte had poor legal assistance at trial, his public defenders said in documents filed with the parole board.
Late Tuesday, the U.S. Supreme Court denied a last-minute request from Otte to delay the execution. Two members of the state execution team did a consciousness check at 10:42.
The state plans to execute the 45-year-old Otte with a lethal combination of three drugs.
Ohio Department of Rehabilitation and Correction spokeswoman JoEllen Smith said in an email that "we followed proper security protocol, and once her identity and intention was verified she was given permission to exit the room". Otte was scheduled to visit with his attorneys, brother and sister and parents.
He was the second inmate put to death since OH ended a three-year execution hiatus prompted by a lethal injection that raised questions about the drugs being used. Otte is not appealing that decision.
Otte is scheduled to die Wednesday in the state death chamber at the Southern Ohio Correctional Facility in Lucasville. His final meal included a mushroom and Swiss cheese hamburger, a quart of Heath Bar ice cream and a slice of banana cream pie.
Journalists who witnessed the execution did not report any apparent problems like the breathing troubles and prolonged deaths that have occurred during some other lethal injections.
Otte unsuccessfully challenged the use of midazolam, the first drug in the state's procedure, which was involved in problematic executions in Arizona and Oklahoma.